Performance Comparison of Hollow Fiber Membrane Contactors for Liquid-Liquid Extraction of Penicillin-G from Wastewater
Document Type : Research Paper
Authors
- 1 PhD Scholar, Department of Chemical Engineering, Faculty of Chemical Engineering, Shiraz Branch, Islamic Azad University, Shiraz, Iran
- 2 Assoc. Professor, Department of Chemical Engineering, Membrane Science and Technology Research Center (MSTRC), Gachsaran Branch, Islamic Azad University, Gachsaran, Iran
- 3 Assist. Professor, Department of Chemical Engineering, Faculty of Chemical Engineering, Shiraz Branch, Islamic Azad University, Shiraz, Iran
Abstract
Pharmaceutical waste is one of the considerable problems of the environment. Membrane contactors are used to treat various of wastewater. This study compared the effectiveness of polyvinylidene fluoride-hexafluoropropylene (PVDF-HFP) and polysulfone (PSF) membrane contactors in separating antibiotics from pharmaceutical wastewater. For this purpose, PVDF-HFP hollow fiber membranes were prepared using the non-solvent phase separation (NIPS) method. Hollow fiber membranes were characterized. Penicillin G was extracted from pharmaceutical wastewater with a liquid-liquid membrane contacting system. Optimizing the operational variables of penicillin G extraction was done using the response surface method. The results showed that the PVDF-HFP membrane has an open structure with large finger-like cavities, fragile outer skin, and an inner skinless layer. This membrane has an average surface pore size, total porosity, and water contact angle of 0.04 µm, 84%, and 94°, respectively. PVDF-HFP membrane showed the maximum penicillin G extraction flux of 1.54 × 10-3 kg/m2s in the optimal operating conditions of aqueous phase flow rate of 51 ml/min and organic phase flow rate of 144 ml/min. By comparing the characteristics and using the response surface method, it was determined that the PVDF-HFP membrane contactor has a higher extraction flux than PSF in separating penicillin G from pharmaceutical wastewater.
Keywords
Subjects
Water Pollution
Abbasi-Sourki, F., Mansourizadeh, A., & Jazebizadeh, M. H. (2023). Liquid-Liquid extraction of penicillin-g from pharmaceutical wastewater via a developed polysulfone hollow fiber membrane contactor. Environ. Water Eng., 9(2), 179–194. DOI: 10.22034/ewe.2022.350118.1798.
Abbasi-Sourki, F., Jazebizadeh, M. H., Mansourizadeh, A., Hojjati, M. R. )2021(. Extraction of penicillin-G from pharmaceutical wastewaters via a developed hydrophobic PVDF-HFP hollow fiber membrane contactor and process optimization. Environ. Technol. Innovation., 22,101426. DOI: 10.1016/j.eti.2021.101406.
Abbasi, M. A., Ali, Z., Qamar, Z., Shahzad, K., Siddiqui, H. K., Atif, M., Ali, Z., & Khalid, W. (2021). Phase pure synthesis of lanthanum doped bismuth ferrite nanostructures for the adsorption of doxorubicin. Int. J. Ceramics., 47(10), 14390-14398. DOI: 10.1016/j.ceramint.2021.02.018
Ahmad, T., Rehman, L. M., Al-Nuaimi, R., Benjamin Boross de Levay, J-P., Thankamony, R., Mubashir, M., & Lai, Z. (2023). Thermodynamics and kinetic analysis of membrane: Challenges and perspectives. Chemosphere., 337, 139430. DOI: 10.1016/j.chemosphere.2023.139430
Bakeri, Gh., Matsuura, T., Ismail, A. F. & Rana, D. (2012). A novel surface-modified polyetherimide hollow fiber membrane for gas-liquid contacting processes. J. Sep. Purif. Technol., 89, 160–170. DOI: 10.1016/j.seppur.2012.01.022
Chuanfang, Yang., & Cussler, E. L. (2000). Reactive extraction of penicillin G in hollow–fiber and hollow-fiber fabric modules. Biotecnol. Bioeng., 69(1). DOI: 10.1002/(sici)1097-0290(20000705)69:1<66::aid-bit8>3.0.co;2-i.
Deb, A., Debnath, A., & Saha, B. (2021). Sono-assisted enhanced adsorption of ferrochrome Black-T dye onto a novel polymeric nanocomposite: Kinetic, isotherm, and response surface methodology optimization. J. Dispers. Sci. Technol., 42(11), 1-14. DOI: 10.1080/01932691.2020.1775093.
Elik, A. (2022). Application of central composite design in parameters optimization of nano-structured supramolecular solvent based on liquid-liquid microextraction to determine total lead in food, vegetables, grilled meat products, and water samples. Sustain. Chem. Pharm.., 29, 100801.DOI: 10.1016/j.scp.2022.100801.
Egea-Corbacho, A., Gutie´rrez Ruiz, S., & Quiroga-Alonso, J. M. (2019). Removal of emerging contaminants from wastewater using nanofiltration for subsequent reuse: Full–scale pilot plant. J. Clean. Prod., 214, 514–523. DOI: 10.1016/j.jclepro.2018.12.297.
FarhadiManesh, M., Mansourizadeh, A., & Honarvar, B. (2019). Fabrication and characterization of developed polysulfone hollow fiber membranes for stream dehumidification A gas in a gas-liquid membrane contactor. J. New Mater., 11(40), 45-58 [in Persian].
Fontananova, E., Jansen, J. C., Cristiano, A., Curcio, E., & Drioli, E. (2006). Effect of Additives in the Casting Solution on the Formation of PVDF Membranes. Desal., 192, 190-197. DOI: 10.1016/j.desal.2005.09.021
Hossain, M., & Dean, J. (2008). Extraction of penicillin G from aqueous solution- reaction equilibrium and mass transfer analysis. Sep. Purif. Tec., 62(2), 437-443. DOI: 10.1016/j.seppur.2008.02.012.
Haghgoo, A. A., Cheraghi, M., Sobhanardakani, S., Lorestani, B., & Izadkhah, V. (2022). Prepare AC/KOH and AC/Fe3O4/ZnO nanocomposite from waste rice straw to remove cyclophosphamide from aqueous solutions. Toxin. Rev., 42(1). DOI: 10.1080/15569543.2022.2124422
Ismail, A. F., & Mansourizadeh, A. (2010). Comparative study on the structure and performance of porous polyvinylidene fluoride and polysulfone hollow fiber membranes for CO2 absorption. J. Membr. Sci., 365(1-2), 319-328. DOI: 10.1016/j.memsci.2010.09.021.
Johari, A., Razmjouei, M., Mansourizadeh, A. & Emadzadeh, D. (2020). Fabrication blends hydrophilic polyamide-imide (Torlon®)-sulfonated poly (ether ether ketone) hollow fiber membranes for oily wastewater treatment. J. Polymer Test., 91. DOI: 10.1016/j.polymertesting.2020.106733.
Kong, J., & Li, K. (2001). Preparation of PVDF Hollow-Fiber Membranes via Immersion Precipitation. J. Appl. Polym. Sci., 81, 1643-1653. DOI: 10.1002/app.1595.abs
Lazarova, Z. (2002). Application of large-scale hollow fiber membrane contactors for simultaneous extractive removal and stripping of penicillin G. J. Membrane Sci., 202(1-2), 151-164. DOI: 10.1016/s0376-7388(01)00748-7.
Lee, S. C. (2004). Kinetics of reactive extraction of penicillin G by Amberlite LA-2 in kerosene. AlchEJ., 50, 119-126. DOI: 10.1002/aic.10011.
Mansourizadeh, A., Rezaei, I., Lau, W. J., Seah, M. Q., & Ismail, A. F. (2022). A review on recent progress in environmental applications of membrane contactor technology. J. Environ. Chem. Eng., 10(3), 107631. DOI: 10.1016/j.jece.2022.107631.
Mansourizadeh, A., & Ismail, A. F. (2011). Preparation and characterization of porous PVDF hollow fiber membranes for CO2 absorption: Effect of different non-solvent additives in the polymer dope. Int. J. Greenh. Gas Control., 5, 640–648. DOI: 10.1016/j.ijggc.
Mousavi, S. A., Arab Aboosadi, Z., Mansourizadeh, A., & Honarvar, B. (2021a). Surface-modified porous polyetherimide hollow fiber membrane for sweeping gas membrane distillation of dyeing wastewater. Colloid Surf. A., 610, 125439. DOI: 10.1016/j.colsurfa.2020.125439.
Mousavi, S. A., ArabAboosadi, Z., Mansourizadeh, A., & Honarvar, B. (2021b). Modification of porous polyetherimide hollow fiber membrane by dip-coating of Zonyl® BA for membrane distillation of dyeing wastewater. Water Sci. Technol., 83(12), 3092-3102. DOI: 10.2166/wst.2021.201.
Richardson, B. J., Lam, P. K. S., & Martin, M. (2005). Emerging chemicals of concern: Pharmaceuticals and personal care products (PPCPs) in Asia, with particular reference to Southern China. Mar. Pollut. Bull., 50 (9), 913–920. DOI: 10.1016/j.marpolbul.2005.06.034.
Rahimpour, A., Jahanshahi, M., Rajaeian, B., & Rahimnejad, M. (2018). TiO2 entrapped nano-composite PVDF/SPES membranes: preparation, characterization, antifouling, and antibacterial properties. J. Desal., 278(1-3), 343–353. DOI: 10.1016/j.desal.2011.05.049.
Rahbari-Sisakht, M., Ismail, A. F. & Matsuura, T. (2012). Effect of bore fluid composition on structure and performance of asymmetric polysulfone hollow fiber membrane contactor for CO2 absorption. J. Sep. Purif. Technol., 88, 99-106. DOI: 10.1016/j.seppur.2011.12.012.
Rehman, W. U., Muhammad, A., Younas, M., Wu, C., Hu, Y., & Li, J. (2019). Effect of membrane wetting on the performance of PVDF and PTFE membranes in the concentration of pomegranate juice through osmotic distillation. J. Membr. Sci., 584, 66–78. DOI: 10.1016/j.memsci.2019.04.042.
Smith, E., & Hossain, M. (2007). Extraction and recovery of penicillin G in a hollow-fiber membrane contactor. Asia-Pacific, J. Chem. Eng., DOI: 10.1002/apj.81.
Sarkar, B. Mandal, S., Tsang, Y. F., Kumar, P., Kim, K. H., & Ok, Y. S. (2018). Designer carbon nanotubes for contaminant removal in water and wastewater: A critical review. Sci. Total Environ., 612, 561–581. DOI: 10.1016/j.scitotenv.2017.08.132.
SobhanArdakani. S., Cheraghi. M., Jafari. A., & Zandipak. R. (2020). PECVD synthesis of ZnO/Si thin film as a novel adsorbent for removal of azithromycin from water samples. Int. J. Environ. Analyt. Chem., 102(17). DOI: 10.1080/03067319.2020.1793973.
Sayerh, F., Mouhir, L., Saafadi, L., & Khazraji, M. (2023). Review of hospital effluents: special emphasis on characterization, impact, and treatment of pollutants and antibiotic resistance. Environ. Monit. Assess., 195, 393. DOI: 10.1007/s10661-023-11002-5
Tong, D., Wang, X., Ali, M., Q-Lan, C., Wang, Y., Drioli, E., Wang, Z., & Cui, Z. (2015). Preparation of Hyflon AD60/PVDF composite hollow fiber membranes for vacuum membrane distillation. J. Sep. Purif. Technol., 157. 1–8. DOI: 10.1016/j.seppur.2015.11.026
Wang, D., Li, K., & Teo, W K. (2000). Porous PVDF asymmetric hollow fiber membranes prepared with the use of small molecular additives. J. Membr. Sci., 178, 13–23. DOI: 10.1016/s0376-7388(00)00460-9.
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